Effects of the mechanical field in cells on cell migration
Elucidation of the mechanism of force transmission through the cytoskeleton
||Research Subjects and Results
Forces generated by cytoskeleton are believed to contribute to cellular dynamical processes like migration.
Stress fibers including actin bundles and myosins at rear of cells generate contraction forces which propel the cell body to move forward during migration.
We proposeed a method for measuring local tensions in SFs and showed that the method actually measured the tensions in SFs.
Real time measurement of tension in SFs in live cell
||VCAD Public Software
Software Block Page
S. Sugita, T. Murase, N. Sakamoto, T. Ohashi, and M. Sato
°÷Size sorting of kinesin-driven microtubules with topographical grooves on a chip,°◊
Lab on a Chip 10(6), 755?761, 2010.
S. Sugita, T. Adachi, Y. Ueki, and M. Sato
°÷Direct measurement of tension generated in cytoskeleton,°◊
6th World Congress on Biomechanics, Singapore, 2010.8.1?6
Selected Publications Page